Dr Anthony Martin, Non-Executive Chairman

Dr Martin has a long history of creating substantial value in the life sciences arena. Dr Martin is also the Chairman of Wound Solutions Ltd., a director of the Prelude Trust and a director of Protedyne Corporation, a US based life sciences company. Previously he has been Chairman of NeuTec Pharma, President and CEO of Molecular Probes Inc., President of Molecular Biology for Invitrogen Corporation and President and CEO of Invitrogen B.V. Between 1995 and 2000, he was Chairman and CEO of AZUR Environmental Inc. Before this, he was Chief Executive of Celsis International plc and Chairman of Tepnel Life Sciences plc.

Dr Stuart Hendry, CEO, Director

Dr Hendry has 20 years experience in the medical device industry, having held positions at Pfizer Hospital Products, Diametrics Inc, PowderJect plc and the Generics Group plc. He has been involved in the commercialisation of numerous medical devices, many in the area of clinical monitoring and diagnostics. He is on the board of ERBI Ltd and Chairman of the Medilink Steering Group, a member of the CBI SME Council and member of the Healthcare KTN Steering Group.

Dr Ann Simon, Chief Financial Officer

Dr Simon has worked in finance, particularly in the healthcare and technology sectors, since 1985. She has been CFO of Genosis PLC, finance director of Mirada Solutions, NextGen Sciences, e-San and Bioglan Pharma, prior to which she was at Cazenove & Co.

Richard P Lyman, Non-Executive Director
Oakes Lyman & Co.

Mr Lyman is a Managing Director of Oakes, Lyman & Co. Limited. Additionally, in his corporate career he was President of Squibb's Medical Systems International Group. In his career in venture capital he formed a number of start-up companies including Biotechnology General Inc. (where he was Chairman and CEO), Life Technologies - now Invitrogen Corporation (Chairman and CEO), Medimmune Inc (Director), Genetic Therapy Inc. (Chairman), Osteotech Inc. (Chairman) and Quadrant Healthcareplc (Chairman and CEO).

Dr William Mason, Non-Executive Director

For 20 years, Dr Mason led an internationally recognised medical research group in Cambridge. During this time, he founded Life Science Resources, now part of Perkin Elmer, and Communication Resources, now part of Leo Burnett. He is a board member of several privately funded healthcare companies as well as companies quoted on the London Stock Exchange and NASDAQ. He also founded Sage Healthcare, a specialist boutique for bio and health transactions. He is a Member of the 3i plc Independent Directors Programme.

Bob Pettigrew, Non-Executive Director

Mr Pettigrew has more than 20 years experience in the development of emerging businesses having been a director and investor of a number of growth oriented companies over this period. In 1986 he co-founded Generics which has grown rapidly to become one of the leading technology consulting and investment groups and was key member of the team that took the company public in December 2000. He also was involved in developing Generics investment activities in early stage technology ventures and was a director of the group investment company Generics Asset Management. He retired from Generics at the end of 2002 to pursue independent investment activities. He is an investor director on the board of a number of technology companies including Sphere Medical, BioWisdom, Zinwave, Oxonica, Timberpost and Digital Health Care. He was Chairman of Voxar Ltd and managed its $50m trade sale in Sept 2004. He is a member of the advisory boards of Antenova, the Synergy Fund as well as being a non executive board member of two Venture Capital Trusts listed on the London Stock Exchange.

Ian Paling, Non-Executive Director

Mr Paling has extensive experience of working at senior executive levels within the medical devices sector. He was CEO of Corin Group PLC until the end of 2007, having been with the company through private ownership and then leading a highly successful IPO on the main market of the LSE in May 2002. Whilst at Corin, Mr Paling was instrumental in securing high profile distribution agreements, setting up profitable overseas subsidiaries and directing an acquisition strategy. Throughout his career he has been involved in manufacturing environments, predominantly in the life sciences sector, and brings a wealth of business experience relevant to Sphere.

Audit Committee,

The Audit Committee consists of Dr William Mason (Chairman), Ian Paling and Richard Lyman.

Remuneration Committee,

The Remuneration Committee consists of Dr Anthony Martin (Chairman), Dr William Mason and Bob Pettigrew.

Nominations Committee,

The Nominations Committee consists of Dr Anthony Martin (Chairman), Dr Stuart Hendry, Richard Lyman and Bob Pettigrew.