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Sphere has brought together a robust portfolio of patented technologies, focussed on addressing clear unmet clinical needs. Our technologies support a broad range of measurements in any physiological fluid, including blood, plasma, urine, cerebrospinal fluid and dialysate.
Microfabricated Transducers
Sphere’s transducer technology consists of an integrated circuit or ‘chip’ capable of simultaneously measuring a number of drugs and dissolved gases. Chips are designed to contain a range of transducers, which are modified by the deposition of suitable receptors, to enable the measurement of a number of key patient health parameters to be assessd in real time.
The specific advantages of Sphere’s technology for critical care diagnostic applications include:
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The sensors are small, fast, robust and stable, allowing them to be integrated into arterial, venous and other existing fluid lines to give real time measurements of many parameters simultaneously. |
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Very low sample volumes are required and all or most of the withdrawn sample can be returned to the patient. In a critical care setting, blood sampling contributes to a high level of anaemia and blood transfusion requirements. |
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The chips are manufactured using conventional semiconductor processes, thereby facilitating extremely high levels of product quality and reliability. |
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The sensors are based on a common transducer platform, allowing new test parameters to be added at low cost and variants for specific applications to be developed easily and cheaply. |
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Receptor Materials
Receptors materials used by Sphere range from chemically selective membranes to biomolecules and novel synthetic materials, such as molecularly imprinted polymers.
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